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Great Dane Puppies & Dogs For Sale in Middlesex, North Carolina

Discover from over 25 available Great Dane Puppies / Dogs currently listed for sale across Middlesex, NC on PetzLover! We've added 1+ new listings this week, and you can explore available Great Dane Puppies / Dogs. Based on your current search criteria, you're viewing Great Dane Puppies / Dogs with prices/fees ranging from $250 – $1,200. These include Great Dane Puppies / Dogs typically 5.0 months – 13.0 years old, with approximately 18 males and 9 female, many of which are AKC, UKC-registrable or come from AKC, UKC-registered parents available in Middlesex, NC and surrounding areas. Find your perfect companion from trusted local breeders and reputable rescues, with many offering safe, convenient shipping or transportation options. Secure your perfect companion today!

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AKC GREAT DANE PUPPIES
$1,100
For Sale

AKC GREAT DANE PUPPIES

Dejavudanes30+ days ago

AKC REGISTERED GREAT DANE PUPPIES. Born 1/22/17. Ready to go home March 20, 2017. Puppies..

Great Dane Puppy
iMiddlesex, North CarolinaMiddlesex, North Carolina
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Great Dane puppies
$800
For Sale
Male

Great Dane puppies

Seth Jones30+ days ago

Puppies are vaxed, wormed, dewclawed, microchipped. PM for info. They are ready for homes..

Great Dane Puppy
iClayton, Johnston County, North CarolinaClayton, North Carolina
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Blue great dane puppies
$600
For Sale

Blue great dane puppies

brandon branch30+ days ago

We have 4 blue great dane puppies born sept. 15 2025 2 males and 2 females. The dad is bl..

Great Dane Puppy
iHickory, Catawba County, North CarolinaHickory, North Carolina
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3 month old Great Dane puppy
$750
For Sale

3 month old Great Dane puppy

PetzLover User30+ days ago

Thor is three months old with all of his appropriate shots. He is really sweet but a litt..

Great Dane Puppy
iCharlotte, Mecklenburg County, North CarolinaCharlotte, North Carolina
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5 month old Dane
$800
For Sale

5 month old Dane

Terri30+ days ago

Make Dane pup 6 thumbnailMake Dane pup 7 thumbnailMake Dane pup 8 thumbnail Stop flaggin..

Great Dane Puppy
iPfafftown, Forsyth County, North CarolinaPfafftown, North Carolina
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Make Dane harlequin puppy
$800
For Sale

Make Dane harlequin puppy

Terri30+ days ago

Make Great Dane. Very smart and livable. Thinks he’s a lapdog. Goes to doggy daycare so..

Great Dane Puppy
iPfafftown, Forsyth County, North CarolinaPfafftown, North Carolina
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Rehome Great Dane
$300
For Sale

Rehome Great Dane

mckelvinl30+ days ago

Beautiful sweet 2year old intact, housebroken Merle female current on shots. Serious inqu..

Great Dane Puppy
iWalkertown, Forsyth County, North CarolinaWalkertown, North Carolina
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Daniff puppies
$300
For Sale

Daniff puppies

Tressa Pease30+ days ago

We had an accidental litter of daniff puppies. Mom is English mastiff and dad is great da..

Great Dane Puppy
iFort Liberty, Cumberland County, North CarolinaFort Liberty, North Carolina
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Premium
A friend for life !
For Rehoming

A friend for life !

Tamara Pasin

mako is a very sweet and loyal dog. He is very well trained and will follow you everywher..

Australian Shepherd Puppy
iWilmington, New Hanover County, North CarolinaWilmington, North Carolina
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purebred Great Dane puppies
$1,000
For Sale

purebred Great Dane puppies

Zoe Cullifer30+ days ago

These adorable purebred babies are 50% American, 50% European Great Dane. Both mom and da..

Great Dane Puppy
iWilson, Wilson County, North CarolinaWilson, North Carolina
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Three males left
$250
For Sale

Three males left

Tim Cunningham30+ days ago

I have three male Great Danes full blooded I took them as a rescue as the mother quit nur..

Great Dane Puppy
iIndian Trail, Union County, North CarolinaIndian Trail, North Carolina
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Selling my Great Dane
$900
For Sale

Selling my Great Dane

Polly Ballard30+ days ago

With a heavy Heart we have to sell our Presious Merle Great Dane. She is 10 months old, s..

Great Dane Puppy
iRaeford, Hoke County, North CarolinaRaeford, North Carolina
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Ckc Great Dane puppies
For Sale

Ckc Great Dane puppies

Kacie30+ days ago

CKC Great Dane Puppies born 11/29/24 2 blue females available, have been dewormed and ha..

Great Dane Puppy
iSmithfield, Smithfield, Johnston County, North CarolinaSmithfield, North Carolina
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Mini Goldendoodle Puppies
$1,500
For Sale
Female

Mini Goldendoodle Puppies

Kelli Jones

Wonderful F1BB Mini Goldendoodle puppies. Have mom and dad onsite. Dad is registered mini..

Golden Doodle Puppy
iGibsonville, North CarolinaGibsonville, North Carolina
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Great Dane litter
$1,200
For Sale

Great Dane litter

Lorianne chambers30+ days ago

900 for black and 1200 for the others. Located in **...

Great Dane Puppy
iWaynesville, Waynesville, Haywood County, North CarolinaWaynesville, North Carolina
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AKC Male Pomeranian
$2,500
For Sale
Male

AKC Male Pomeranian

Cheryl kingston

Meet the love of your life, Looking for spunky, outgoing, and all around adorable littl..

Pomeranian Puppy
iHumansville, Washington Township, Cedar County, MissouriWashington Township, Missouri
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Male German Shepherd Puppy CKC
$850
For Sale
Male

Male German Shepherd Puppy CKC

Karol Gonzalez

Male black and tan GSD ready for a good loving home.Pup is very calm, plays well with chi..

German Shepherd Puppy
iLive Oak, Suwannee County, FloridaLive Oak, Florida
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Premium
Dark Traditional male Yorkie
$2,200
For Sale
Male

Dark Traditional male Yorkie

Brenda L Smith

Such a handsome boy, he is becoming very playful and lovable. His markings are perfect. H..

Yorkshire Terrier Puppy
iJarratt, Sussex County, VirginiaJarratt, Virginia
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Premium
Sweet small tri color parti Yorkie boy
$2,200
For Sale
Male

Sweet small tri color parti Yorkie boy

Brenda L Smith

He has the most unique colors n markings. I love he's mostly black with white on his legs..

Yorkshire Terrier Puppy
iJarratt, Sussex County, VirginiaJarratt, Virginia
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Premium
Small, Beautiful Yorkshire terrier puppy
$2,200
For Sale
Female

Small, Beautiful Yorkshire terrier puppy

Brenda L Smith

She is a unique chocolate Merle Yorkie with unique markings. Small, short frame. Mom n da..

Yorkshire Terrier Puppy
iJarratt, Sussex County, VirginiaJarratt, Virginia
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Hades/Persephone 01/22/26
$1,200
For Sale
Female

Hades/Persephone 01/22/26

Jennifer

Dad Male 10/22 Mom Female 7/24 Own Both. STOCK/ Short hair/black & Tan 5 male 4 femal..

German Shepherd Puppy
iChesapeake, VirginiaChesapeake, Virginia
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Premium
Beautiful Kb black tiny female Yorkie
$2,200
For Sale
Female

Beautiful Kb black tiny female Yorkie

Brenda L Smith

She is beautiful and soft. Her fur is soft. She has tiny features. Will be under 5lbs...

Yorkshire Terrier Puppy
iJarratt, Sussex County, VirginiaJarratt, Virginia
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GERMAN SHEPHERD PUPPIES
$500
For Sale
Male

GERMAN SHEPHERD PUPPIES

KWOODY ACRES

4 MALES AND ONE FEMALE 'MOM AND DAD ON PREMISES, BOTH HAVE HAD HIP X RAY AND MICRO CHIPPE..

German Shepherd Puppy
iBlacksburg, Montgomery County, VirginiaBlacksburg, Virginia
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Premium
Small Beautiful chocolate parti female Yorkie
$2,200
For Sale
Female

Small Beautiful chocolate parti female Yorkie

Brenda L Smith

She has unique chocolate parti markings, short snout n legs. Tiny features. Super soft fu..

Yorkshire Terrier Puppy
iJarratt, Sussex County, VirginiaJarratt, Virginia
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Premium
Beautiful tri color parti female Yorkie
$2,200
For Sale
Female

Beautiful tri color parti female Yorkie

Brenda L Smith

She has very unique markings and beautiful colors. Tiny girl which will stay small. Moms ..

Yorkshire Terrier Puppy
iJarratt, Sussex County, VirginiaJarratt, Virginia
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